Free-energy-basedactivation probabilities

Species

p

D

G (kcal/mol)

Species

p

D

G (kcal/mol)

0.017

2.37

0.003

3.55

0.125

1.18

0.017

2.37

0.500

0.00

0.125

1.18

0.874

-1.18

0.500

0.00

0.997

-3.55

0.980

-2.37

Non-ligand bound

Ligand bound

Previous slide

Next slide

Back to first slide

View graphic version